Arginine methyltransferase activity in chronic erythremic myelosis (Diguglielmo syndrome).
نویسندگان
چکیده
Activity of S-adenosylmethionine-dependent arginine methyltransferase was substantially higher in sonicated bone marrow samples from 6 patients with chronic erythremic myelosis than in bone marrow from 3 patients with untreated pernicious anemia, 2 patients with autoimmune hemolytic anemia, and 4 normal persons. Increased activity of this enzyme may be one of the factors contributing to the pathogenesis fo methylated arginines in histones of erythroblasts from patients with chronic erythremic myelosis.
منابع مشابه
5-Methyltetrahydrofolate-dependent methyltransferase activity in chronic erythremic myelosis and other types of anemias.
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characterized by a systemic and irreversible disorder of red cell precursors. Most of the previous papers have dealt with the morphology and histogenesis of the erythremic cells. Reports on the functional and biochemical behavior of these cells are very scanty. Astaldi and Tolentino2 in 1949 and Blackburn and Lajtha3 in 1951, with the method of bone marrow culture in vitro, were able to demonst...
متن کاملRadioautographic Investigations on DNA and Protein
characterized by a systemic and irreversible disorder of red cell precursors. Most of the previous papers have dealt with the morphology and histogenesis of the erythremic cells. Reports on the functional and biochemical behavior of these cells are very scanty. Astaldi and Tolentino2 in 1949 and Blackburn and Lajtha3 in 1951, with the method of bone marrow culture in vitro, were able to demonst...
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عنوان ژورنال:
- Biochimica et biophysica acta
دوره 524 2 شماره
صفحات -
تاریخ انتشار 1978